PDB Information

PDB4C62
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Discovery of 1-Methyl-1H-Imidazole Derivatives as Potent Jak2 Inhibitors.
Su, Q., Ioannidis, S., Chuaqui, C., Almeida, L., Alimzhanov, M., Bebernitz, G., Bell, K., Block, M., Howard, T., Huang, S., Huszar, D., Read, J.A., Rivard Costa, C., Shi, J., Su, M., Ye, M., Zinda, M.
J.Med.Chem.
HeaderTransferase
Released2013-09-17
Resolution2.750
CATH Insert Date02 Feb, 2014

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 03 Feb, 2014 Chopped
B 03 Feb, 2014 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4c62A01 07 Mar, 2014 3.30.200.20 Assigned
4c62A02 07 Mar, 2014 1.10.510.10 Assigned
4c62B01 07 Mar, 2014 3.30.200.20 Assigned
4c62B02 07 Mar, 2014 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O60674 JAK2_HUMAN Homo sapiens Tyrosine-protein kinase JAK2
O60674 JAK2_HUMAN Homo sapiens Tyrosine-protein kinase JAK2