PDB Information

PDB4BMM
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceTRYPANOSOMA CRUZI
Primary Citation
4-Aminopyridyl-Based Cyp51 Inhibitors as Anti-Trypanosoma Cruzi Drug Leads with Improved Pharmacokinetic Profile and in Vivo Potency.
Calvet, C.M., Vieira, D.F., Choi, J.Y., Kellar, D., Cameron, M.D., Siqueira-Neto, J.L., Gut, J., Johnston, J.B., Lin, L., Khan, S., Mckerrow, J.H., Roush, W.R., Podust, L.M.
J.Med.Chem.
HeaderOxidoreductase
Released2013-05-09
Resolution2.840
CATH Insert Date29 Jun, 2014

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 30 Jun, 2014 Chopped
B 30 Jun, 2014 Chopped
C 30 Jun, 2014 Chopped
D 30 Jun, 2014 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4bmmA00 03 Jul, 2014 1.10.630.10 Assigned
4bmmB00 03 Jul, 2014 1.10.630.10 Assigned
4bmmC00 03 Jul, 2014 1.10.630.10 Assigned
4bmmD00 02 Jul, 2014 1.10.630.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q7Z1V1 CP51_TRYCC Trypanosoma cruzi strain CL Brener Sterol 14-alpha demethylase
Q7Z1V1 CP51_TRYCC Trypanosoma cruzi strain CL Brener Sterol 14-alpha demethylase
Q7Z1V1 CP51_TRYCC Trypanosoma cruzi strain CL Brener Sterol 14-alpha demethylase
Q7Z1V1 CP51_TRYCC Trypanosoma cruzi strain CL Brener Sterol 14-alpha demethylase