PDB Information

PDB4BAE
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceMYCOBACTERIUM SMEGMATIS
Primary Citation
Optimization of Pyrrolamides as Mycobacterial Gyrb ATPase Inhibitors: Structure Activity Relationship and in Vivo Efficacy in the Mouse Model of Tuberculosis.
Hameed, S.P., Solapure, S., Mukherjee, K., Nandi, V., Waterson, D., Shandil, R., Balganesh, M., Sambandamurthy, V.K., Raichurkar, A.K., Deshpande, A., Ghosh, A., Awasthy, D., Shanbhag, G., Sheikh, G., Mcmiken, H., Puttur, J., Reddy, J., Werngren, J., Read, J., Kumar, M., Manjunatha, R., Chinnapattu, M., Madhavapeddi, P., Manjrekar, P., Basu, R., Gaonkar, S., Sharma, S., Hoffner, S., Humnabadkar, V., Subbulakshmi, V., Panduga, V.
Antimicrob.Agents Chemother.
HeaderIsomerase
Released2012-09-13
Resolution2.350
CATH Insert Date03 Nov, 2013

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 04 Nov, 2013 Chopped
B 04 Nov, 2013 Chopped
C 04 Nov, 2013 Chopped
D 04 Nov, 2013 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4baeA00 06 Nov, 2013 3.30.565.10 Assigned
4baeB00 08 Nov, 2013 3.30.565.10 Assigned
4baeC00 08 Nov, 2013 3.30.565.10 Assigned
4baeD00 08 Nov, 2013 3.30.565.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P0C559 GYRB_MYCSM Mycolicibacterium smegmatis DNA gyrase subunit B
P0C559 GYRB_MYCSM Mycolicibacterium smegmatis DNA gyrase subunit B
P0C559 GYRB_MYCSM Mycolicibacterium smegmatis DNA gyrase subunit B
P0C559 GYRB_MYCSM Mycolicibacterium smegmatis DNA gyrase subunit B