PDB 4axm

PDB Information

PDB4AXM
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Optimization of Triazine Nitriles as Rhodesain Inhibitors: Structure-Activity Relationships, Bioisosteric Imidazopyridine Nitriles, and X-Ray Crystal Structure Analysis with Human Cathepsin L
Ehmke, V., Winkler, E., Banner, D.W., Haap, W., Schweizer, W.B., Rottmann, M., Kaiser, M., Freymond, C., Schirmeister, T., Diederich, F.
Chemmedchem
HeaderHydrolase
Released2012-06-13
Resolution2.800
CATH Insert Date07 Jul, 2013

PDB Images (13)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 08 Jul, 2013 Chopped
B 08 Jul, 2013 Chopped
F 08 Jul, 2013 Chopped
I 08 Jul, 2013 Chopped
L 08 Jul, 2013 Chopped
O 08 Jul, 2013 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4axmA00 09 Aug, 2013 3.90.70.10 Assigned
4axmB00 09 Aug, 2013 3.90.70.10 Assigned
4axmF00 09 Aug, 2013 3.90.70.10 Assigned
4axmI00 09 Aug, 2013 3.90.70.10 Assigned
4axmL00 09 Aug, 2013 3.90.70.10 Assigned
4axmO00 09 Aug, 2013 3.90.70.10 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
P07711 CATL1_HUMAN Homo sapiens Cathepsin L1
P07711 CATL1_HUMAN Homo sapiens Cathepsin L1
P07711 CATL1_HUMAN Homo sapiens Cathepsin L1
P07711 CATL1_HUMAN Homo sapiens Cathepsin L1
P07711 CATL1_HUMAN Homo sapiens Cathepsin L1
P07711 CATL1_HUMAN Homo sapiens Cathepsin L1