PDB Information

PDB4ANW
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHOMO SAPIENS
Primary Citation
The Discovery of a Novel Series of Potent and Orally Bioavailable Phosphoinositide 3-Kinase Gamma Inhibitors
Leahy, J.W., Buhr, C.A., Johnson, H.W.B., Kim, B.G., Baik, T., Cannoy, J., Forsyth, T.P., Jeong, J.W., Lee, M.S., Ma, S., Noson, K., Wang, L., Williams, M., Nuss, J.M., Brooks, E., Heald, N., Holst, C., Jaeger, C., Lam, S., Lougheed, J.C., Nguyen, L., Plonowski, A., Stout, T., Foster, P.G., Wu, X., Yakes, M.F., Yu, R., Zhang, W., Lamb, P., Raeber, O.
J.Med.Chem.
HeaderTransferase
Released2012-03-22
Resolution2.310
CATH Insert Date27 May, 2012

PDB Images (7)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 28 May, 2012 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
4anwA01 08 Jun, 2012 3.10.20.90 Assigned
4anwA02 08 Jun, 2012 2.60.40.150 Assigned
4anwA03 08 Jun, 2012 1.25.40.70 Assigned
4anwA04 08 Jun, 2012 3.30.1010.10 Assigned
4anwA05 08 Jun, 2012 1.10.1070.11 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P48736 PK3CG_HUMAN Homo sapiens Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
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