PDB Information

PDB4ACD
MethodX-RAY DIFFRACTION
Host OrganismTRICHOPLUSIA NI
Gene SourceHOMO SAPIENS
Primary Citation
Discovery of novel potent and highly selective glycogen synthase kinase-3 beta (GSK3 beta ) inhibitors for Alzheimer's disease: design, synthesis, and characterization of pyrazines.
Berg, S., Bergh, M., Hellberg, S., Hogdin, K., Lo-Alfredsson, Y., Soderman, P., von Berg, S., Weigelt, T., Ormo, M., Xue, Y., Tucker, J., Neelissen, J., Jerning, E., Nilsson, Y., Bhat, R.
J. Med. Chem.
HeaderTransferase
Released2011-12-15
Resolution2.600
CATH Insert Date27 May, 2012

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 28 May, 2012 Chopped
B 28 May, 2012 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4acdA01 08 Jun, 2012 3.30.200.20 Assigned
4acdA02 08 Jun, 2012 1.10.510.10 Assigned
4acdB01 08 Jun, 2012 3.30.200.20 Assigned
4acdB02 08 Jun, 2012 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P49841 GSK3B_HUMAN Homo sapiens Glycogen synthase kinase-3 beta
P49841 GSK3B_HUMAN Homo sapiens Glycogen synthase kinase-3 beta