PDB Information

PDB4A4L
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHOMO SAPIENS
Primary Citation
5-(2-Amino-Pyrimidin-4-Yl)-1H-Pyrrole and 2-(2-Amino-Pyrimidin-4-Yl)-1,5,6,7-Tetrahydro-Pyrrolo[3,2-C]Pyridin-4-One Derivatives as New Classes of Selective and Orally Available Polo-Like Kinase 1 Inhibitors.
Caruso, M., Valsasina, B., Ballinari, D., Bertrand, J.A., Brasca, M.G., Caldarelli, M., Cappella, P., Fiorentini, F., Gianellini, L.M., Scolaro, A., Beria, I.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2011-10-17
Resolution2.350
CATH Insert Date15 Jan, 2012

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 16 Jan, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4a4lA01 19 Jan, 2012 3.30.200.20 Assigned
4a4lA02 19 Jan, 2012 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P53350 PLK1_HUMAN Homo sapiens Serine/threonine-protein kinase PLK1