PDB Information

PDB3ZEP
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHOMO SAPIENS
Primary Citation
Discovery of a Series of Novel 5H-Pyrrolo[2,3-B]Pyrazine-2-Phenyl Ethers, as Potent Jak3 Kinase Inhibitors.
Jaime-Figueroa, S., De Vicente, J., Hermann, J., Jahangir, A., Jin, S., Kuglstatter, A., Lynch, S.M., Menke, J., Niu, L., Patel, V., Shao, A., Soth, M., Vu, M.D., Yee, C.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2012-12-06
Resolution2.350
CATH Insert Date15 Dec, 2013

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 16 Dec, 2013 Chopped
B 16 Dec, 2013 Chopped
C 16 Dec, 2013 Chopped
D 16 Dec, 2013 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3zepA01 20 Dec, 2013 3.30.200.20 Assigned
3zepA02 20 Dec, 2013 1.10.510.10 Assigned
3zepB01 20 Dec, 2013 3.30.200.20 Assigned
3zepB02 20 Dec, 2013 1.10.510.10 Assigned
3zepC01 20 Dec, 2013 3.30.200.20 Assigned
3zepC02 20 Dec, 2013 1.10.510.10 Assigned
3zepD01 20 Dec, 2013 3.30.200.20 Assigned
3zepD02 20 Dec, 2013 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P52333 JAK3_HUMAN Homo sapiens Tyrosine-protein kinase JAK3
P52333 JAK3_HUMAN Homo sapiens Tyrosine-protein kinase JAK3
P52333 JAK3_HUMAN Homo sapiens Tyrosine-protein kinase JAK3
P52333 JAK3_HUMAN Homo sapiens Tyrosine-protein kinase JAK3
CATH-Gene3D is a Global Biodata Core Resource Learn more...