PDB 3ws8
PDB Information
PDB | 3WS8 |
Method | X-RAY DIFFRACTION |
Host Organism | Escherichia coli |
Gene Source | Homo sapiens |
Primary Citation | Novel benzimidazole derivatives as phosphodiesterase 10A (PDE10A) inhibitors with improved metabolic stability.
Bioorg.Med.Chem.
|
Header | Hydrolase/Hydrolase Inhibitor |
Released | 2014-03-04 |
Resolution | 2.600 |
CATH Insert Date | 15 Jun, 2014 |
PDB Images (5)
PDB Prints
PDB Chains (2)
Chain ID | Date inserted into CATH | CATH Status |
---|---|---|
A | 16 Jun, 2014 | Chopped |
B | 16 Jun, 2014 | Chopped |
CATH Domains (2)
Domain ID | Date inserted into CATH | Superfamily | CATH Status |
---|---|---|---|
3ws8A00 | 18 Jun, 2014 | 1.10.1300.10 | Assigned |
3ws8B00 | 18 Jun, 2014 | 1.10.1300.10 | Assigned |
UniProtKB Entries (2)
Accession | Gene ID | Taxon | Description |
---|---|---|---|
Q9Y233 | PDE10_HUMAN | Homo sapiens | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A |
Q9Y233 | PDE10_HUMAN | Homo sapiens | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A |