PDB Information

PDB3VZV
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Lead optimization of novel p53-MDM2 interaction inhibitors possessing dihydroimidazothiazole scaffold
Miyazaki, M., Naito, H., Sugimoto, Y., Kawato, H., Okayama, T., Shimizu, H., Miyazaki, M., Kitagawa, M., Seki, T., Fukutake, S., Aonuma, M., Soga, T.
Bioorg.Med.Chem.Lett.
HeaderLigase/Ligase Inhibitor
Released2012-10-16
Resolution2.800
CATH Insert Date28 Mar, 2013

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 28 Mar, 2013 Chopped
B 28 Mar, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3vzvA00 10 Apr, 2013 1.10.245.10 Assigned
3vzvB00 10 Apr, 2013 1.10.245.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2
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