PDB Information

PDB3VUC
MethodX-RAY DIFFRACTION
Host OrganismHomo sapiens
Gene SourceHomo sapiens
Primary Citation
Discovery of DS-8108b, a Novel Orally Bioavailable Renin Inhibitor.
Nakamura, Y., Fujimoto, T., Ogawa, Y., Sugita, C., Miyazaki, S., Tamaki, K., Takahashi, M., Matsui, Y., Nagayama, T., Manabe, K., Mizuno, M., Masubuchi, N., Chiba, K., Nishi, T.
Acs Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2012-06-26
Resolution2.600
CATH Insert Date07 Jul, 2013

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 Jul, 2013 Chopped
B 08 Jul, 2013 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3vucA01 04 Nov, 2013 2.40.70.10 Assigned
3vucA02 04 Nov, 2013 2.40.70.10 Assigned
3vucB01 04 Nov, 2013 2.40.70.10 Assigned
3vucB02 04 Nov, 2013 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P00797 RENI_HUMAN Homo sapiens Renin
P00797 RENI_HUMAN Homo sapiens Renin