PDB Information

PDB3VBG
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization.
Graves, B., Thompson, T., Xia, M., Janson, C., Lukacs, C., Deo, D., Di Lello, P., Fry, D., Garvie, C., Huang, K.S., Gao, L., Tovar, C., Lovey, A., Wanner, J., Vassilev, L.T.
Proc.Natl.Acad.Sci.USA
HeaderLigase/Ligase Activator
Released2012-01-02
Resolution2.800
CATH Insert Date04 Nov, 2012

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped
B 05 Nov, 2012 Chopped
C 05 Nov, 2012 Chopped
D 05 Nov, 2012 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3vbgA00 10 Nov, 2012 1.10.245.10 Assigned
3vbgB00 10 Nov, 2012 1.10.245.10 Assigned
3vbgC00 10 Nov, 2012 1.10.245.10 Assigned
3vbgD00 10 Nov, 2012 1.10.245.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2