PDB 3v8t

PDB Links
Overview

PDB Information

PDB	3V8T
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	X-ray crystallographic structure-based design of selective thienopyrazole inhibitors for interleukin-2-inducible tyrosine kinase. McLean, L.R., Zhang, Y., Zaidi, N., Bi, X., Wang, R., Dharanipragada, R., Jurcak, J.G., Gillespy, T.A., Zhao, Z., Musick, K.Y., Choi, Y.M., Barrague, M., Peppard, J., Smicker, M., Duguid, M., Parkar, A., Fordham, J., Kominos, D. Bioorg.Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2011-12-23
Resolution	2.000
CATH Insert Date	27 May, 2012

PDB Images (7)

Image of CATH 3v8t

3v8t

PDB 3v8t

Image of CATH 3v8tA

3v8tA

PDB Chain 3v8tA

Image of CATH 3v8tB

3v8tB

PDB Chain 3v8tB

Image of CATH 3v8tA01

3v8tA01

CATH Domain 3v8tA01

Image of CATH 3v8tA02

3v8tA02

CATH Domain 3v8tA02

Image of CATH 3v8tB01

3v8tB01

CATH Domain 3v8tB01

Image of CATH 3v8tB02

3v8tB02

CATH Domain 3v8tB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	28 May, 2012	Chopped
B	28 May, 2012	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3v8tA01	08 Jun, 2012	3.30.200.20	Assigned
3v8tA02	08 Jun, 2012	1.10.510.10	Assigned
3v8tB01	08 Jun, 2012	3.30.200.20	Assigned
3v8tB02	08 Jun, 2012	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q08881	ITK_HUMAN	Homo sapiens	Tyrosine-protein kinase ITK/TSK
Q08881	ITK_HUMAN	Homo sapiens	Tyrosine-protein kinase ITK/TSK