PDB 3v7t

PDB Information

PDB3V7T
MethodX-RAY DIFFRACTION
Host OrganismKomagataella pastoris
Gene SourceHomo sapiens
Primary Citation
A beta-tryptase inhibitor with a tropanylamide scaffold to improve in vitro stability and to lower hERG channel binding affinity
Liang, G., Choi-Sledeski, Y.M., Shum, P., Chen, X., Poli, G.B., Kumar, V., Minnich, A., Wang, Q., Tsay, J., Sides, K., Kang, J., Zhang, Y.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2011-12-22
Resolution2.090
CATH Insert Date27 May, 2012

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 28 May, 2012 Chopped
B 28 May, 2012 Chopped
C 28 May, 2012 Chopped
D 28 May, 2012 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3v7tA01 08 Jun, 2012 2.40.10.10 Assigned
3v7tA02 08 Jun, 2012 2.40.10.10 Assigned
3v7tB01 08 Jun, 2012 2.40.10.10 Assigned
3v7tB02 08 Jun, 2012 2.40.10.10 Assigned
3v7tC01 08 Jun, 2012 2.40.10.10 Assigned
3v7tC02 08 Jun, 2012 2.40.10.10 Assigned
3v7tD01 08 Jun, 2012 2.40.10.10 Assigned
3v7tD02 08 Jun, 2012 2.40.10.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P20231 TRYB2_HUMAN Homo sapiens Tryptase beta-2
P20231 TRYB2_HUMAN Homo sapiens Tryptase beta-2
P20231 TRYB2_HUMAN Homo sapiens Tryptase beta-2
P20231 TRYB2_HUMAN Homo sapiens Tryptase beta-2