PDB Information

PDB3V6O
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure of the human obesity receptor leptin-binding domain reveals the mechanism of leptin antagonism by a monoclonal antibody.
Carpenter, B., Hemsworth, G.R., Wu, Z., Maamra, M., Strasburger, C.J., Ross, R.J., Artymiuk, P.J.
Structure
HeaderImmune System
Released2011-12-20
Resolution1.950
CATH Insert Date27 May, 2012

PDB Images (19)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 28 May, 2012 Chopped
B 28 May, 2012 Chopped
C 28 May, 2012 Chopped
D 28 May, 2012 Chopped
E 28 May, 2012 Chopped
F 28 May, 2012 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
3v6oA01 18 Apr, 2013 2.60.40.10 Assigned
3v6oA02 18 Apr, 2013 2.60.40.10 Assigned
3v6oB01 18 Apr, 2013 2.60.40.10 Assigned
3v6oB02 18 Apr, 2013 2.60.40.10 Assigned
3v6oC01 08 Jun, 2012 2.60.40.10 Assigned
3v6oC02 08 Jun, 2012 2.60.40.10 Assigned
3v6oD01 08 Jun, 2012 2.60.40.10 Assigned
3v6oD02 08 Jun, 2012 2.60.40.10 Assigned
3v6oE01 08 Jun, 2012 2.60.40.10 Assigned
3v6oE02 08 Jun, 2012 2.60.40.10 Assigned
3v6oF01 08 Jun, 2012 2.60.40.10 Assigned
3v6oF02 08 Jun, 2012 2.60.40.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P48357 LEPR_HUMAN Homo sapiens Leptin receptor
P48357 LEPR_HUMAN Homo sapiens Leptin receptor
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