PDB Information

PDB3UGC
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Modulation of activation-loop phosphorylation by JAK inhibitors is binding mode dependent.
Andraos, R., Qian, Z., Bonenfant, D., Rubert, J., Vangrevelinghe, E., Scheufler, C., Marque, F., Regnier, C.H., De Pover, A., Ryckelynck, H., Bhagwat, N., Koppikar, P., Goel, A., Wyder, L., Tavares, G., Baffert, F., Pissot-Soldermann, C., Manley, P.W., Gaul, C., Voshol, H., Levine, R.L., Sellers, W.R., Hofmann, F., Radimerski, T.
Cancer Discov
HeaderTransferase/Transferase Inhibitor
Released2011-11-02
Resolution1.340
CATH Insert Date27 May, 2012

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 28 May, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3ugcA01 08 Jun, 2012 3.30.200.20 Assigned
3ugcA02 08 Jun, 2012 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O60674 JAK2_HUMAN Homo sapiens Tyrosine-protein kinase JAK2