PDB 3udj

PDB Information

PDB3UDJ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery and optimization of a novel spiropyrrolidine inhibitor of {beta}-secretase (BACE1) through fragment-based drug design.
Efremov, I.V., Vajdos, F.F., Borzilleri, K.A., Capetta, S., Chen, H., Dorff, P.H., Dutra, J.K., Goldstein, S.W., Mansour, M., McColl, A., Noell, S., Oborski, C.E., O'Connell, T.N., O'Sullivan, T.J., Pandit, J., Wang, H., Wei, B., Withka, J.M.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2011-10-28
Resolution1.800
CATH Insert Date27 May, 2012

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 28 May, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3udjA01 08 Jun, 2012 2.40.70.10 Assigned
3udjA02 08 Jun, 2012 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1