PDB 3u2z

PDB Information

PDB3U2Z
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis.
Anastasiou, D., Yu, Y., Israelsen, W.J., Jiang, J.K., Boxer, M.B., Hong, B.S., Tempel, W., Dimov, S., Shen, M., Jha, A., Yang, H., Mattaini, K.R., Metallo, C.M., Fiske, B.P., Courtney, K.D., Malstrom, S., Khan, T.M., Kung, C., Skoumbourdis, A.P., Veith, H., Southall, N., Walsh, M.J., Brimacombe, K.R., Leister, W., Lunt, S.Y., Johnson, Z.R., Yen, K.E., Kunii, K., Davidson, S.M., Christofk, H.R., Austin, C.P., Inglese, J., Harris, M.H., Asara, J.M., Stephanopoulos, G., Salituro, F.G., Jin, S., Dang, L., Auld, D.S., Park, H.W., Cantley, L.C., Thomas, C.J., Vander Heiden, M.G.
Nat.Chem.Biol.
HeaderTransferase/Transferase Activator
Released2011-10-04
Resolution2.100
CATH Insert Date04 Nov, 2012

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped
B 05 Nov, 2012 Chopped
C 05 Nov, 2012 Chopped
D 05 Nov, 2012 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
3u2zA01 08 Feb, 2013 3.40.1380.20 Assigned
3u2zA02 08 Feb, 2013 3.20.20.60 Assigned
3u2zA03 08 Feb, 2013 2.40.33.10 Assigned
3u2zB01 08 Feb, 2013 3.40.1380.20 Assigned
3u2zB02 08 Feb, 2013 3.20.20.60 Assigned
3u2zB03 08 Feb, 2013 2.40.33.10 Assigned
3u2zC01 08 Feb, 2013 3.40.1380.20 Assigned
3u2zC02 08 Feb, 2013 3.20.20.60 Assigned
3u2zC03 08 Feb, 2013 2.40.33.10 Assigned
3u2zD01 08 Feb, 2013 3.40.1380.20 Assigned
3u2zD02 08 Feb, 2013 3.20.20.60 Assigned
3u2zD03 08 Feb, 2013 2.40.33.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P14618 KPYM_HUMAN Homo sapiens Pyruvate kinase PKM
P14618 KPYM_HUMAN Homo sapiens Pyruvate kinase PKM
P14618 KPYM_HUMAN Homo sapiens Pyruvate kinase PKM
P14618 KPYM_HUMAN Homo sapiens Pyruvate kinase PKM