PDB Information

PDB3U0T
MethodX-RAY DIFFRACTION
Host OrganismHomo sapiens
Gene SourceHomo sapiens
Primary Citation
Structural Basis of C-terminal beta-Amyloid Peptide Binding by the Antibody Ponezumab for the Treatment of Alzheimer's Disease
La Porte, S.L., Bollini, S.S., Lanz, T.A., Abdiche, Y.N., Rusnak, A.S., Ho, W.H., Kobayashi, D., Harrabi, O., Pappas, D., Mina, E.W., Milici, A.J., Kawabe, T.T., Bales, K., Lin, J.C., Pons, J.
J.Mol.Biol.
HeaderImmune System
Released2011-09-29
Resolution2.500
CATH Insert Date15 Jan, 2012

PDB Images (15)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 16 Jan, 2012 Chopped
B 16 Jan, 2012 Chopped
C 16 Jan, 2012 Chopped
D 16 Jan, 2012 Chopped
E 16 Jan, 2012 Rejected
F 16 Jan, 2012 Rejected

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3u0tA01 19 Jan, 2012 2.60.40.10 Assigned
3u0tA02 19 Jan, 2012 2.60.40.10 Assigned
3u0tB01 19 Jan, 2012 2.60.40.10 Assigned
3u0tB02 19 Jan, 2012 2.60.40.10 Assigned
3u0tC01 19 Jan, 2012 2.60.40.10 Assigned
3u0tC02 19 Jan, 2012 2.60.40.10 Assigned
3u0tD01 19 Jan, 2012 2.60.40.10 Assigned
3u0tD02 19 Jan, 2012 2.60.40.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P05067 A4_HUMAN Homo sapiens Amyloid-beta precursor protein
P05067 A4_HUMAN Homo sapiens Amyloid-beta precursor protein
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