PDB 3tyv

PDB Information

PDB3TYV
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHepatitis C virus
Primary Citation
Structure-Activity Relationship (SAR) Development and Discovery of Potent Indole-Based Inhibitors of the Hepatitis C Virus (HCV) NS5B Polymerase.
Chen, K.X., Vibulbhan, B., Yang, W., Sannigrahi, M., Velazquez, F., Chan, T.Y., Venkatraman, S., Anilkumar, G.N., Zeng, Q., Bennet, F., Jiang, Y., Lesburg, C.A., Duca, J., Pinto, P., Gavalas, S., Huang, Y., Wu, W., Selyutin, O., Agrawal, S., Feld, B., Huang, H.C., Li, C., Cheng, K.C., Shih, N.Y., Kozlowski, J.A., Rosenblum, S.B., Njoroge, F.G.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2011-09-26
Resolution1.650
CATH Insert Date05 Feb, 2012

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 06 Feb, 2012 Chopped
B 06 Feb, 2012 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3tyvA01 08 Oct, 2013 Holding pen
3tyvA02 08 Oct, 2013 Holding pen
3tyvB01 08 Oct, 2013 Holding pen
3tyvB02 08 Oct, 2013 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O92972 POLG_HCVJ4 Hepatitis C virus isolate HC-J4 Genome polyprotein
O92972 POLG_HCVJ4 Hepatitis C virus isolate HC-J4 Genome polyprotein