PDB 3tv7

PDB Information

PDB3TV7
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Pyridylthiazole-based ureas as inhibitors of Rho associated protein kinases (ROCK1 and 2).
Pireddu, R., Forinash, K.D., Sun, N.N., Martin, M.P., Sung, S.S., Alexander, B., Zhu, J.Y., Guida, W.C., Schonbrunn, E., Sebti, S.M., Lawrence, N.J.
Medchemcomm
HeaderTransferase/Transferase Inhibitor
Released2011-09-19
Resolution2.750
CATH Insert Date19 Feb, 2012

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 20 Feb, 2012 Chopped
B 20 Feb, 2012 Chopped
C 20 Feb, 2012 Chopped
D 20 Feb, 2012 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3tv7A01 08 Feb, 2013 3.30.200.20 Assigned
3tv7A02 08 Feb, 2013 1.10.510.10 Assigned
3tv7B01 08 Feb, 2013 3.30.200.20 Assigned
3tv7B02 08 Feb, 2013 1.10.510.10 Assigned
3tv7C01 08 Feb, 2013 3.30.200.20 Assigned
3tv7C02 08 Feb, 2013 1.10.510.10 Assigned
3tv7D01 08 Feb, 2013 3.30.200.20 Assigned
3tv7D02 08 Feb, 2013 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q13464 ROCK1_HUMAN Homo sapiens Rho-associated protein kinase 1
Q13464 ROCK1_HUMAN Homo sapiens Rho-associated protein kinase 1
Q13464 ROCK1_HUMAN Homo sapiens Rho-associated protein kinase 1
Q13464 ROCK1_HUMAN Homo sapiens Rho-associated protein kinase 1