PDB Information

PDB3TJD
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of potent and highly selective thienopyridine janus kinase 2 inhibitors.
Schenkel, L.B., Huang, X., Cheng, A., Deak, H.L., Doherty, E., Emkey, R., Gu, Y., Gunaydin, H., Kim, J.L., Lee, J., Loberg, R., Olivieri, P., Pistillo, J., Tang, J., Wan, Q., Wang, H.L., Wang, S.W., Wells, M.C., Wu, B., Yu, V., Liu, L., Geuns-Meyer, S.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2011-08-24
Resolution2.900
CATH Insert Date04 Dec, 2011

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Dec, 2011 Chopped
B 05 Dec, 2011 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3tjdA01 07 Dec, 2011 3.30.200.20 Assigned
3tjdA02 07 Dec, 2011 1.10.510.10 Assigned
3tjdB01 07 Dec, 2011 3.30.200.20 Assigned
3tjdB02 07 Dec, 2011 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O60674 JAK2_HUMAN Homo sapiens Tyrosine-protein kinase JAK2
O60674 JAK2_HUMAN Homo sapiens Tyrosine-protein kinase JAK2