PDB 3tcp

PDB Information

PDB3TCP
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of Novel Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic Leukemia.
Liu, J., Yang, C., Simpson, C., Deryckere, D., Van Deusen, A., Miley, M.J., Kireev, D., Norris-Drouin, J., Sather, S., Hunter, D., Korboukh, V.K., Patel, H.S., Janzen, W.P., Machius, M., Johnson, G.L., Earp, H.S., Graham, D.K., Frye, S.V., Wang, X.
ACS Med Chem Lett
HeaderTransferase/Transferase Inhibitor
Released2011-08-09
Resolution2.690
CATH Insert Date24 Jun, 2012

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 24 Jun, 2012 Chopped
B 24 Jun, 2012 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3tcpA01 28 Jun, 2012 3.30.200.20 Assigned
3tcpA02 28 Jun, 2012 1.10.510.10 Assigned
3tcpB01 28 Jun, 2012 3.30.200.20 Assigned
3tcpB02 28 Jun, 2012 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q12866 MERTK_HUMAN Homo sapiens Tyrosine-protein kinase Mer
Q12866 MERTK_HUMAN Homo sapiens Tyrosine-protein kinase Mer