PDB Information

PDB3T70
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourcePlasmodium falciparum
Primary Citation
Design, synthesis, and evaluation of 5'-diphenyl nucleoside analogues as inhibitors of the Plasmodium falciparum dUTPase.
Hampton, S.E., Baragana, B., Schipani, A., Bosch-Navarrete, C., Musso-Buendia, J.A., Recio, E., Kaiser, M., Whittingham, J.L., Roberts, S.M., Shevtsov, M., Brannigan, J.A., Kahnberg, P., Brun, R., Wilson, K.S., Gonzalez-Pacanowska, D., Johansson, N.G., Gilbert, I.H.
Chemmedchem
HeaderHydrolase/Hydrolase Inhibitor
Released2011-07-29
Resolution1.800
CATH Insert Date04 Nov, 2012

PDB Images (8)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped
B 05 Nov, 2012 Chopped
C 05 Nov, 2012 Chopped
F 05 Nov, 2012 Rejected

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
3t70A01 10 Nov, 2012 2.70.40.10 Assigned
3t70B01 10 Nov, 2012 2.70.40.10 Assigned
3t70C01 10 Nov, 2012 2.70.40.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
Q8II92 Q8II92_PLAF7 Plasmodium falciparum 3D7 Deoxyuridine 5'-triphosphate nucleotidohydrolase
Q8II92 Q8II92_PLAF7 Plasmodium falciparum 3D7 Deoxyuridine 5'-triphosphate nucleotidohydrolase
Q8II92 Q8II92_PLAF7 Plasmodium falciparum 3D7 Deoxyuridine 5'-triphosphate nucleotidohydrolase
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