PDB Information

PDB3SZ9
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of a novel class of covalent inhibitor for aldehyde dehydrogenases.
Khanna, M., Chen, C.H., Kimble-Hill, A., Parajuli, B., Perez-Miller, S., Baskaran, S., Kim, J., Dria, K., Vasiliou, V., Mochly-Rosen, D., Hurley, T.D.
J.Biol.Chem.
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2011-07-18
Resolution2.100
CATH Insert Date06 Nov, 2011

PDB Images (25)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 29 Nov, 2011 Chopped
B 29 Nov, 2011 Chopped
C 29 Nov, 2011 Chopped
D 29 Nov, 2011 Chopped
E 29 Nov, 2011 Chopped
F 29 Nov, 2011 Chopped
G 29 Nov, 2011 Chopped
H 29 Nov, 2011 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
3sz9A01 01 Dec, 2011 3.40.605.10 Assigned
3sz9A02 01 Dec, 2011 3.40.309.10 Assigned
3sz9B01 01 Dec, 2011 3.40.605.10 Assigned
3sz9B02 01 Dec, 2011 3.40.309.10 Assigned
3sz9C01 01 Dec, 2011 3.40.605.10 Assigned
3sz9C02 01 Dec, 2011 3.40.309.10 Assigned
3sz9D01 01 Dec, 2011 3.40.605.10 Assigned
3sz9D02 01 Dec, 2011 3.40.309.10 Assigned
3sz9E01 01 Dec, 2011 3.40.605.10 Assigned
3sz9E02 01 Dec, 2011 3.40.309.10 Assigned
3sz9F01 01 Dec, 2011 3.40.605.10 Assigned
3sz9F02 01 Dec, 2011 3.40.309.10 Assigned
3sz9G01 01 Dec, 2011 3.40.605.10 Assigned
3sz9G02 01 Dec, 2011 3.40.309.10 Assigned
3sz9H01 01 Dec, 2011 3.40.605.10 Assigned
3sz9H02 01 Dec, 2011 3.40.309.10 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
P05091 ALDH2_HUMAN Homo sapiens Aldehyde dehydrogenase, mitochondrial
P05091 ALDH2_HUMAN Homo sapiens Aldehyde dehydrogenase, mitochondrial
P05091 ALDH2_HUMAN Homo sapiens Aldehyde dehydrogenase, mitochondrial
P05091 ALDH2_HUMAN Homo sapiens Aldehyde dehydrogenase, mitochondrial
P05091 ALDH2_HUMAN Homo sapiens Aldehyde dehydrogenase, mitochondrial
P05091 ALDH2_HUMAN Homo sapiens Aldehyde dehydrogenase, mitochondrial
P05091 ALDH2_HUMAN Homo sapiens Aldehyde dehydrogenase, mitochondrial
P05091 ALDH2_HUMAN Homo sapiens Aldehyde dehydrogenase, mitochondrial