PDB Information

PDB3SMR
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5.
Senisterra, G., Wu, H., Allali-Hassani, A., Wasney, G.A., Barsyte-Lovejoy, D., Dombrovski, L., Dong, A., Nguyen, K.T., Smil, D., Bolshan, Y., Hajian, T., He, H., Seitova, A., Chau, I., Li, F., Poda, G., Couture, J.F., Brown, P.J., Al-Awar, R., Schapira, M., Arrowsmith, C.H., Vedadi, M.
Biochem. J.
HeaderTranscription
Released2011-06-28
Resolution1.820
CATH Insert Date04 Sep, 2011

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 Sep, 2011 Chopped
B 05 Sep, 2011 Chopped
C 05 Sep, 2011 Chopped
D 05 Sep, 2011 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3smrA00 17 Jul, 2013 2.130.10.10 Assigned
3smrB00 17 Jul, 2013 2.130.10.10 Assigned
3smrC00 17 Jul, 2013 2.130.10.10 Assigned
3smrD00 17 Jul, 2013 2.130.10.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P61964 WDR5_HUMAN Homo sapiens WD repeat-containing protein 5
P61964 WDR5_HUMAN Homo sapiens WD repeat-containing protein 5
P61964 WDR5_HUMAN Homo sapiens WD repeat-containing protein 5
P61964 WDR5_HUMAN Homo sapiens WD repeat-containing protein 5