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PDB Information
| PDB | 3S3V |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation |
Crystallographic analysis reveals a novel second binding site for trimethoprim in active site double mutants of human dihydrofolate reductase.
Cody, V., Pace, J., Piraino, J., Queener, S.F.
J.Struct.Biol.
|
| Header | Oxidoreductase/Oxidoreductase Inhibitor |
| Released | 2011-05-18 |
| Resolution | 1.530 |
| CATH Insert Date | 02 Oct, 2011 |
PDB Images (3)
3s3vA00
CATH Domain 3s3vA00
PDB Chains (1)
| Chain ID | Date inserted into CATH | CATH Status |
| A | 29 Nov, 2011 | Chopped
|
CATH Domains (1)
UniProtKB Entries (1)
| Accession |
Gene ID |
Taxon |
Description |
| P00374 |
DYR_HUMAN |
Homo sapiens |
Dihydrofolate reductase |