PDB Information

PDB3RHX
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
A novel mode of protein kinase inhibition exploiting hydrophobic motifs of autoinhibited kinases: discovery of ATP-independent inhibitors of fibroblast growth factor receptor.
Eathiraj, S., Palma, R., Hirschi, M., Volckova, E., Nakuci, E., Castro, J., Chen, C.R., Chan, T.C., France, D.S., Ashwell, M.A.
J.Biol.Chem.
HeaderTransferase/Transferase Inhibitor
Released2011-04-12
Resolution2.010
CATH Insert Date08 May, 2011

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 09 May, 2011 Chopped
B 09 May, 2011 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3rhxA01 15 May, 2011 3.30.200.20 Assigned
3rhxA02 15 May, 2011 1.10.510.10 Assigned
3rhxB01 15 May, 2011 3.30.200.20 Assigned
3rhxB02 15 May, 2011 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P11362 FGFR1_HUMAN Homo sapiens Fibroblast growth factor receptor 1
P11362 FGFR1_HUMAN Homo sapiens Fibroblast growth factor receptor 1