PDB Information

PDB3RBM
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourcePlasmodium vivax
Primary Citation
Lipophilic analogs of zoledronate and risedronate inhibit Plasmodium geranylgeranyl diphosphate synthase (GGPPS) and exhibit potent antimalarial activity.
No, J.H., de Macedo Dossin, F., Zhang, Y., Liu, Y.L., Zhu, W., Feng, X., Yoo, J.A., Lee, E., Wang, K., Hui, R., Freitas-Junior, L.H., Oldfield, E.
Proc.Natl.Acad.Sci.USA
HeaderTransferase/Transferase Inhibitor
Released2011-03-29
Resolution2.610
CATH Insert Date27 May, 2012

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 28 May, 2012 Chopped
B 28 May, 2012 Chopped
C 28 May, 2012 Chopped
D 28 May, 2012 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3rbmA00 08 Jun, 2012 1.10.600.10 Assigned
3rbmB00 08 Jun, 2012 1.10.600.10 Assigned
3rbmC00 08 Jun, 2012 1.10.600.10 Assigned
3rbmD00 08 Jun, 2012 1.10.600.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
A5K4U6 A5K4U6_PLAVS Plasmodium vivax Sal-1 Farnesyl pyrophosphate synthase, putative
A5K4U6 A5K4U6_PLAVS Plasmodium vivax Sal-1 Farnesyl pyrophosphate synthase, putative
A5K4U6 A5K4U6_PLAVS Plasmodium vivax Sal-1 Farnesyl pyrophosphate synthase, putative
A5K4U6 A5K4U6_PLAVS Plasmodium vivax Sal-1 Farnesyl pyrophosphate synthase, putative