PDB 3r92

PDB Links
Overview

PDB Information

PDB	3R92
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of a macrocyclic o-aminobenzamide Hsp90 inhibitor with heterocyclic tether that shows extended biomarker activity and in vivo efficacy in a mouse xenograft model. Zapf, C.W., Bloom, J.D., McBean, J.L., Dushin, R.G., Golas, J.M., Liu, H., Lucas, J., Boschelli, F., Vogan, E., Levin, J.I. Bioorg.Med.Chem.Lett.
Header	Chaperone/Chaperone Inhibitor
Released	2011-03-24
Resolution	1.580
CATH Insert Date	12 Jun, 2011

PDB Images (3)

Image of CATH 3r92

3r92

PDB 3r92

Image of CATH 3r92A

3r92A

PDB Chain 3r92A

Image of CATH 3r92A00

3r92A00

CATH Domain 3r92A00

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	13 Jun, 2011	Chopped

CATH Domains (1)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3r92A00	30 Aug, 2013	3.30.565.10	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P07900	HS90A_HUMAN	Homo sapiens	Heat shock protein HSP 90-alpha