PDB 3qpn

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Overview

PDB Information

PDB	3QPN
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Rattus norvegicus
Primary Citation	Use of Structure-Based Design to Discover a Potent, Selective, In Vivo Active Phosphodiesterase 10A Inhibitor Lead Series for the Treatment of Schizophrenia. Helal, C.J., Kang, Z., Hou, X., Pandit, J., Chappie, T.A., Humphrey, J.M., Marr, E.S., Fennell, K.F., Chenard, L.K., Fox, C., Schmidt, C.J., Williams, R.D., Chapin, D.S., Siuciak, J., Lebel, L., Menniti, F., Cianfrogna, J., Fonseca, K.R., Nelson, F.R., O'Connor, R., Macdougall, M., McDowell, L., Liras, S. J.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2011-02-14
Resolution	2.000
CATH Insert Date	19 Jun, 2011

PDB Images (3)

Image of CATH 3qpn

3qpn

PDB 3qpn

Image of CATH 3qpnA

3qpnA

PDB Chain 3qpnA

Image of CATH 3qpnA00

3qpnA00

CATH Domain 3qpnA00

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	20 Jun, 2011	Chopped

CATH Domains (1)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3qpnA00	08 Feb, 2013	1.10.1300.10	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
Q9QYJ6	PDE10_RAT	Rattus norvegicus	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A