PDB 3qc4

PDB Links
Overview

PDB Information

PDB	3QC4
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Discovery of a potent and highly selective PDK1 inhibitor via fragment-based drug discovery. Erlanson, D.A., Arndt, J.W., Cancilla, M.T., Cao, K., Elling, R.A., English, N., Friedman, J., Hansen, S.K., Hession, C., Joseph, I., Kumaravel, G., Lee, W.C., Lind, K.E., McDowell, R.S., Miatkowski, K., Nguyen, C., Nguyen, T.B., Park, S., Pathan, N., Penny, D.M., Romanowski, M.J., Scott, D., Silvian, L., Simmons, R.L., Tangonan, B.T., Yang, W., Sun, L. Bioorg.Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2011-01-15
Resolution	1.800
CATH Insert Date	24 Apr, 2011

PDB Images (7)

Image of CATH 3qc4

3qc4

PDB 3qc4

Image of CATH 3qc4A

3qc4A

PDB Chain 3qc4A

Image of CATH 3qc4B

3qc4B

PDB Chain 3qc4B

Image of CATH 3qc4A01

3qc4A01

CATH Domain 3qc4A01

Image of CATH 3qc4A02

3qc4A02

CATH Domain 3qc4A02

Image of CATH 3qc4B01

3qc4B01

CATH Domain 3qc4B01

Image of CATH 3qc4B02

3qc4B02

CATH Domain 3qc4B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	25 Apr, 2011	Chopped
B	25 Apr, 2011	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3qc4A01	04 May, 2011	3.30.200.20	Assigned
3qc4A02	04 May, 2011	1.10.510.10	Assigned
3qc4B01	29 Aug, 2013	3.30.200.20	Assigned
3qc4B02	29 Aug, 2013	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
O15530	PDPK1_HUMAN	Homo sapiens	3-phosphoinositide-dependent protein kinase 1
O15530	PDPK1_HUMAN	Homo sapiens	3-phosphoinositide-dependent protein kinase 1