PDB 3qbh
PDB Information
PDB | 3QBH |
Method | X-RAY DIFFRACTION |
Host Organism | Escherichia coli |
Gene Source | Homo sapiens |
Primary Citation | Structure based design, synthesis and SAR of cyclic hydroxyethylamine (HEA) BACE-1 inhibitors.
Bioorg.Med.Chem.Lett.
|
Header | Hydrolase/Hydrolase Inhibitor |
Released | 2011-01-13 |
Resolution | 2.240 |
CATH Insert Date | 27 Mar, 2011 |
PDB Images (10)
PDB Prints
PDB Chains (3)
Chain ID | Date inserted into CATH | CATH Status |
---|---|---|
A | 28 Mar, 2011 | Chopped |
B | 28 Mar, 2011 | Chopped |
C | 28 Mar, 2011 | Chopped |
CATH Domains (6)
Domain ID | Date inserted into CATH | Superfamily | CATH Status |
---|---|---|---|
3qbhA01 | 01 Apr, 2011 | 2.40.70.10 | Assigned |
3qbhA02 | 01 Apr, 2011 | 2.40.70.10 | Assigned |
3qbhB01 | 01 Apr, 2011 | 2.40.70.10 | Assigned |
3qbhB02 | 01 Apr, 2011 | 2.40.70.10 | Assigned |
3qbhC01 | 01 Apr, 2011 | 2.40.70.10 | Assigned |
3qbhC02 | 01 Apr, 2011 | 2.40.70.10 | Assigned |
UniProtKB Entries (3)
Accession | Gene ID | Taxon | Description |
---|---|---|---|
P56817 | BACE1_HUMAN | Homo sapiens | Beta-secretase 1 |
P56817 | BACE1_HUMAN | Homo sapiens | Beta-secretase 1 |
P56817 | BACE1_HUMAN | Homo sapiens | Beta-secretase 1 |