PDB 3q4b

PDB Information

PDB3Q4B
MethodX-RAY DIFFRACTION
Host OrganismHomo sapiens
Gene SourceHomo sapiens
Primary Citation
Discovery of VTP-27999, an Alkyl Amine Renin Inhibitor with Potential for Clinical Utility.
Jia, L., Simpson, R.D., Yuan, J., Xu, Z., Zhao, W., Cacatian, S., Tice, C.M., Guo, J., Ishchenko, A., Singh, S.B., Wu, Z., McKeever, B.M., Bukhtiyarov, Y., Johnson, J.A., Doe, C.P., Harrison, R.K., McGeehan, G.M., Dillard, L.W., Baldwin, J.J., Claremon, D.A.
ACS Med Chem Lett
HeaderHydrolase/Hydrolase Inhibitor
Released2010-12-23
Resolution2.190
CATH Insert Date04 Dec, 2011

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Dec, 2011 Chopped
B 05 Dec, 2011 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3q4bA01 04 Nov, 2013 2.40.70.10 Assigned
3q4bA02 04 Nov, 2013 2.40.70.10 Assigned
3q4bB01 04 Nov, 2013 2.40.70.10 Assigned
3q4bB02 04 Nov, 2013 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P00797 RENI_HUMAN Homo sapiens Renin
P00797 RENI_HUMAN Homo sapiens Renin