PDB 3q0z

PDB Information

PDB3Q0Z
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHepatitis C virus subtype 1b
Primary Citation
Syntheses and initial evaluation of a series of indolo-fused heterocyclic inhibitors of the polymerase enzyme (NS5B) of the hepatitis C virus.
Zheng, X., Hudyma, T.W., Martin, S.W., Bergstrom, C., Ding, M., He, F., Romine, J., Poss, M.A., Kadow, J.F., Chang, C.H., Wan, J., Witmer, M.R., Morin, P., Camac, D.M., Sheriff, S., Beno, B.R., Rigat, K.L., Wang, Y.K., Fridell, R., Lemm, J., Qiu, D., Liu, M., Voss, S., Pelosi, L., Roberts, S.B., Gao, M., Knipe, J., Gentles, R.G.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2010-12-16
Resolution2.290
CATH Insert Date08 May, 2011

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 09 May, 2011 Chopped
B 09 May, 2011 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3q0zA01 08 Oct, 2013 Holding pen
3q0zA02 08 Oct, 2013 Holding pen
3q0zB01 08 Oct, 2013 Holding pen
3q0zB02 08 Oct, 2013 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9WMX2 POLG_HCVCO Hepatitis C virus (isolate Con1) Genome polyprotein
Q9WMX2 POLG_HCVCO Hepatitis C virus (isolate Con1) Genome polyprotein