PDB Information

PDB3PLZ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Small Molecule Agonists of the Orphan Nuclear Receptors Steroidogenic Factor-1 (SF-1, NR5A1) and Liver Receptor Homologue-1 (LRH-1, NR5A2).
Whitby, R.J., Stec, J., Blind, R.D., Dixon, S., Leesnitzer, L.M., Orband-Miller, L.A., Williams, S.P., Willson, T.M., Xu, R., Zuercher, W.J., Cai, F., Ingraham, H.A.
J.Med.Chem.
HeaderTranscription/Receptor/Agonist
Released2010-11-15
Resolution1.750
CATH Insert Date03 Apr, 2011

PDB Images (7)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 04 Apr, 2011 Chopped
B 04 Apr, 2011 Chopped
C 04 Apr, 2011 Rejected
D 04 Apr, 2011 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3plzA00 18 Mar, 2013 1.10.565.10 Assigned
3plzB00 07 Feb, 2013 1.10.565.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q15596 NCOA2_HUMAN Homo sapiens Nuclear receptor coactivator 2
O00482 NR5A2_HUMAN Homo sapiens Nuclear receptor subfamily 5 group A member 2
O00482 NR5A2_HUMAN Homo sapiens Nuclear receptor subfamily 5 group A member 2
Q15596 NCOA2_HUMAN Homo sapiens Nuclear receptor coactivator 2