PDB Information

PDB3P11
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
A two-in-one antibody against HER3 and EGFR has superior inhibitory activity compared with monospecific antibodies.
Schaefer, G., Haber, L., Crocker, L.M., Shia, S., Shao, L., Dowbenko, D., Totpal, K., Wong, A., Lee, C.V., Stawicki, S., Clark, R., Fields, C., Lewis Phillips, G.D., Prell, R.A., Danilenko, D.M., Franke, Y., Stephan, J.P., Hwang, J., Wu, Y., Bostrom, J., Sliwkowski, M.X., Fuh, G., Eigenbrot, C.
Cancer Cell
HeaderImmune System
Released2010-09-29
Resolution3.700
CATH Insert Date30 Oct, 2011

PDB Images (11)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 29 Nov, 2011 Chopped
H 29 Nov, 2011 Chopped
L 29 Nov, 2011 Chopped

CATH Domains (7)

Domain ID Date inserted into CATH Superfamily CATH Status
3p11A01 24 Sep, 2013 3.80.20.20 Assigned
3p11A02 24 Sep, 2013 2.10.220.10 Assigned
3p11A03 24 Sep, 2013 3.80.20.20 Assigned
3p11H01 01 Dec, 2011 2.60.40.10 Assigned
3p11H02 01 Dec, 2011 2.60.40.10 Assigned
3p11L01 01 Dec, 2011 2.60.40.10 Assigned
3p11L02 01 Dec, 2011 2.60.40.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P21860 ERBB3_HUMAN Homo sapiens Receptor tyrosine-protein kinase erbB-3
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