PDB Information

PDB3P0Y
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
A two-in-one antibody against HER3 and EGFR has superior inhibitory activity compared with monospecific antibodies.
Schaefer, G., Haber, L., Crocker, L.M., Shia, S., Shao, L., Dowbenko, D., Totpal, K., Wong, A., Lee, C.V., Stawicki, S., Clark, R., Fields, C., Lewis Phillips, G.D., Prell, R.A., Danilenko, D.M., Franke, Y., Stephan, J.P., Hwang, J., Wu, Y., Bostrom, J., Sliwkowski, M.X., Fuh, G., Eigenbrot, C.
Cancer Cell
HeaderImmune System
Released2010-09-29
Resolution1.800
CATH Insert Date30 Oct, 2011

PDB Images (9)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 29 Nov, 2011 Chopped
H 29 Nov, 2011 Chopped
L 29 Nov, 2011 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
3p0yA00 01 Dec, 2011 3.80.20.20 Assigned
3p0yH01 01 Dec, 2011 2.60.40.10 Assigned
3p0yH02 01 Dec, 2011 2.60.40.10 Assigned
3p0yL01 01 Dec, 2011 2.60.40.10 Assigned
3p0yL02 01 Dec, 2011 2.60.40.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor