PDB 3ohh

PDB Information

PDB3OHH
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Synthesis and SAR of indole-and 7-azaindole-1,3-dicarboxamide hydroxyethylamine inhibitors of BACE-1.
Marcin, L.R., Higgins, M.A., Zusi, F.C., Zhang, Y., Dee, M.F., Parker, M.F., Muckelbauer, J.K., Camac, D.M., Morin, P.E., Ramamurthy, V., Tebben, A.J., Lentz, K.A., Grace, J.E., Marcinkeviciene, J.A., Kopcho, L.M., Burton, C.R., Barten, D.M., Toyn, J.H., Meredith, J.E., Albright, C.F., Bronson, J.J., Macor, J.E., Thompson, L.A.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2010-08-17
Resolution2.010
CATH Insert Date10 Apr, 2011

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2011 Chopped
B 11 Apr, 2011 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3ohhA01 20 Nov, 2017 2.40.70.10 Assigned
3ohhA02 20 Nov, 2017 2.40.70.10 Assigned
3ohhB01 20 Nov, 2017 2.40.70.10 Assigned
3ohhB02 20 Nov, 2017 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1