PDB 3oev

PDB Links
Overview

PDB Information

PDB	3OEV
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Optimization of a series of dipeptides with a P3 threonine residue as non-covalent inhibitors of the chymotrypsin-like activity of the human 20S proteasome. Blackburn, C., Barrett, C., Blank, J.L., Bruzzese, F.J., Bump, N., Dick, L.R., Fleming, P., Garcia, K., Hales, P., Hu, Z., Jones, M., Liu, J.X., Sappal, D.S., Sintchak, M.D., Tsu, C., Gigstad, K.M. Bioorg.Med.Chem.Lett.
Header	Hydrolase/Hydrolase Inhibitor
Released	2010-08-13
Resolution	2.850
CATH Insert Date	24 Jul, 2011

PDB Images (57)

3oev

PDB 3oev

3oev1

PDB Chain 3oev1

3oev2

PDB Chain 3oev2

3oevA

PDB Chain 3oevA

3oevB

PDB Chain 3oevB

3oevC

PDB Chain 3oevC

3oevD

PDB Chain 3oevD

3oevE

PDB Chain 3oevE

3oevF

PDB Chain 3oevF

3oevG

PDB Chain 3oevG

3oevH

PDB Chain 3oevH

3oevI

PDB Chain 3oevI

3oevJ

PDB Chain 3oevJ

3oevK

PDB Chain 3oevK

3oevL

PDB Chain 3oevL

3oevM

PDB Chain 3oevM

3oevN

PDB Chain 3oevN

3oevO

PDB Chain 3oevO

3oevP

PDB Chain 3oevP

3oevQ

PDB Chain 3oevQ

3oevR

PDB Chain 3oevR

3oevS

PDB Chain 3oevS

3oevT

PDB Chain 3oevT

3oevU

PDB Chain 3oevU

3oevV

PDB Chain 3oevV

3oevW

PDB Chain 3oevW

3oevX

PDB Chain 3oevX

3oevY

PDB Chain 3oevY

3oevZ

PDB Chain 3oevZ

3oev100

CATH Domain 3oev100

3oev200

CATH Domain 3oev200

3oevA00

CATH Domain 3oevA00

3oevB00

CATH Domain 3oevB00

3oevC00

CATH Domain 3oevC00

3oevD00

CATH Domain 3oevD00

3oevE00

CATH Domain 3oevE00

3oevF00

CATH Domain 3oevF00

3oevG00

CATH Domain 3oevG00

3oevH00

CATH Domain 3oevH00

3oevI00

CATH Domain 3oevI00

3oevJ00

CATH Domain 3oevJ00

3oevK00

CATH Domain 3oevK00

3oevL00

CATH Domain 3oevL00

3oevM00

CATH Domain 3oevM00

3oevN00

CATH Domain 3oevN00

3oevO00

CATH Domain 3oevO00

3oevP00

CATH Domain 3oevP00

3oevQ00

CATH Domain 3oevQ00

3oevR00

CATH Domain 3oevR00

3oevS00

CATH Domain 3oevS00

3oevT00

CATH Domain 3oevT00

3oevU00

CATH Domain 3oevU00

3oevV00

CATH Domain 3oevV00

3oevW00

CATH Domain 3oevW00

3oevX00

CATH Domain 3oevX00

3oevY00

CATH Domain 3oevY00

3oevZ00

CATH Domain 3oevZ00

PDB Prints

PDB Chains (28)

Chain ID	Date inserted into CATH	CATH Status
1	01 Aug, 2011	Chopped
2	01 Aug, 2011	Chopped
A	01 Aug, 2011	Chopped
B	01 Aug, 2011	Chopped
C	01 Aug, 2011	Chopped
D	01 Aug, 2011	Chopped
E	01 Aug, 2011	Chopped
F	01 Aug, 2011	Chopped
G	01 Aug, 2011	Chopped
H	01 Aug, 2011	Chopped
I	01 Aug, 2011	Chopped
J	01 Aug, 2011	Chopped
K	01 Aug, 2011	Chopped
L	01 Aug, 2011	Chopped
M	01 Aug, 2011	Chopped
N	01 Aug, 2011	Chopped
O	01 Aug, 2011	Chopped
P	01 Aug, 2011	Chopped
Q	01 Aug, 2011	Chopped
R	01 Aug, 2011	Chopped
S	01 Aug, 2011	Chopped
T	01 Aug, 2011	Chopped
U	01 Aug, 2011	Chopped
V	01 Aug, 2011	Chopped
W	01 Aug, 2011	Chopped
X	01 Aug, 2011	Chopped
Y	01 Aug, 2011	Chopped
Z	01 Aug, 2011	Chopped

CATH Domains (28)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3oev100	12 Aug, 2011	3.60.20.10	Assigned
3oev200	12 Aug, 2011	3.60.20.10	Assigned
3oevA00	04 Feb, 2013	3.60.20.10	Assigned
3oevB00	04 Feb, 2013	3.60.20.10	Assigned
3oevC00	04 Feb, 2013	3.60.20.10	Assigned
3oevD00	08 Feb, 2013	3.60.20.10	Assigned
3oevE00	12 Aug, 2011	3.60.20.10	Assigned
3oevF00	12 Aug, 2011	3.60.20.10	Assigned
3oevG00	12 Aug, 2011	3.60.20.10	Assigned
3oevH00	12 Aug, 2011	3.60.20.10	Assigned
3oevI00	12 Aug, 2011	3.60.20.10	Assigned
3oevJ00	12 Aug, 2011	3.60.20.10	Assigned
3oevK00	12 Aug, 2011	3.60.20.10	Assigned
3oevL00	12 Aug, 2011	3.60.20.10	Assigned
3oevM00	12 Aug, 2011	3.60.20.10	Assigned
3oevN00	12 Aug, 2011	3.60.20.10	Assigned
3oevO00	04 Feb, 2013	3.60.20.10	Assigned
3oevP00	04 Feb, 2013	3.60.20.10	Assigned
3oevQ00	04 Feb, 2013	3.60.20.10	Assigned
3oevR00	08 Feb, 2013	3.60.20.10	Assigned
3oevS00	12 Aug, 2011	3.60.20.10	Assigned
3oevT00	12 Aug, 2011	3.60.20.10	Assigned
3oevU00	12 Aug, 2011	3.60.20.10	Assigned
3oevV00	12 Aug, 2011	3.60.20.10	Assigned
3oevW00	12 Aug, 2011	3.60.20.10	Assigned
3oevX00	12 Aug, 2011	3.60.20.10	Assigned
3oevY00	12 Aug, 2011	3.60.20.10	Assigned
3oevZ00	12 Aug, 2011	3.60.20.10	Assigned

UniProtKB Entries (28)

Accession	Gene ID	Taxon	Description
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1