PDB 3nzs

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Overview

PDB Information

PDB	3NZS
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Structure-based optimization of pyrazolo-pyrimidine and -pyridine inhibitors of PI3-kinase. Staben, S.T., Heffron, T.P., Sutherlin, D.P., Bhat, S.R., Castanedo, G.M., Chuckowree, I.S., Dotson, J., Folkes, A.J., Friedman, L.S., Lee, L., Lesnick, J., Lewis, C., Murray, J.M., Nonomiya, J., Olivero, A.G., Plise, E., Pang, J., Prior, W.W., Salphati, L., Rouge, L., Sampath, D., Tsui, V., Wan, N.C., Wang, S., Wiesmann, C., Wu, P., Zhu, B.Y. Bioorg.Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2010-07-16
Resolution	2.750
CATH Insert Date	23 Jan, 2011

PDB Images (7)

Image of CATH 3nzs

3nzs

PDB 3nzs

Image of CATH 3nzsA

3nzsA

PDB Chain 3nzsA

Image of CATH 3nzsA01

3nzsA01

CATH Domain 3nzsA01

Image of CATH 3nzsA02

3nzsA02

CATH Domain 3nzsA02

Image of CATH 3nzsA03

3nzsA03

CATH Domain 3nzsA03

Image of CATH 3nzsA04

3nzsA04

CATH Domain 3nzsA04

Image of CATH 3nzsA05

3nzsA05

CATH Domain 3nzsA05

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	24 Jan, 2011	Chopped

CATH Domains (5)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3nzsA01	16 Feb, 2011	3.10.20.90	Assigned
3nzsA02	16 Feb, 2011	2.60.40.150	Assigned
3nzsA03	16 Feb, 2011	1.25.40.70	Assigned
3nzsA04	16 Feb, 2011	3.30.1010.10	Assigned
3nzsA05	16 Feb, 2011	1.10.1070.11	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P48736	PK3CG_HUMAN	Homo sapiens	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform