PDB 3ntz
PDB Information
| PDB | 3NTZ |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation | Design, synthesis, biological evaluation and X-ray crystal structure of novel classical 6,5,6-tricyclic benzo[4,5]thieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors.
Bioorg.Med.Chem.
|
| Header | Oxidoreductase/Oxidoreductase Inhibitor |
| Released | 2010-07-06 |
| Resolution | 1.350 |
| CATH Insert Date | 29 May, 2011 |
PDB Prints
PDB Chains (1)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 30 May, 2011 | Chopped |
CATH Domains (1)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 3ntzA00 | 01 Jun, 2011 | 3.40.430.10 | Assigned |
UniProtKB Entries (1)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P00374 | DYR_HUMAN | Homo sapiens | Dihydrofolate reductase |