PDB Information

PDB3NIG
MethodX-RAY DIFFRACTION
Host OrganismCricetulus griseus
Gene SourceHomo sapiens
Primary Citation
Closed headpiece of integrin {alpha}IIb{beta}3 and its complex with an {alpha}IIb{beta}3-specific antagonist that does not induce opening.
Zhu, J., Zhu, J., Negri, A., Provasi, D., Filizola, M., Coller, B.S., Springer, T.A.
Blood
HeaderCell Adhesion/Blood Clotting
Released2010-06-15
Resolution2.250
CATH Insert Date23 Jan, 2011

PDB Images (25)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 24 Jan, 2011 Chopped
B 24 Jan, 2011 Chopped
C 24 Jan, 2011 Chopped
D 24 Jan, 2011 Chopped
E 24 Jan, 2011 Chopped
F 24 Jan, 2011 Chopped
H 24 Jan, 2011 Chopped
L 24 Jan, 2011 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
3nigA00 17 Feb, 2011 2.130.10.130 Assigned
3nigB01 04 Jul, 2013 3.30.1680.10 Assigned
3nigB02 04 Jul, 2013 2.60.40.1510 Assigned
3nigB03 04 Jul, 2013 3.40.50.410 Assigned
3nigC00 17 Feb, 2011 2.130.10.130 Assigned
3nigD01 04 Jul, 2013 3.30.1680.10 Assigned
3nigD02 04 Jul, 2013 2.60.40.1510 Assigned
3nigD03 04 Jul, 2013 3.40.50.410 Assigned
3nigE01 17 Feb, 2011 2.60.40.10 Assigned
3nigE02 17 Feb, 2011 2.60.40.10 Assigned
3nigF01 17 Feb, 2011 2.60.40.10 Assigned
3nigF02 17 Feb, 2011 2.60.40.10 Assigned
3nigH01 17 Feb, 2011 2.60.40.10 Assigned
3nigH02 17 Feb, 2011 2.60.40.10 Assigned
3nigL01 17 Feb, 2011 2.60.40.10 Assigned
3nigL02 17 Feb, 2011 2.60.40.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P08514 ITA2B_HUMAN Homo sapiens Integrin alpha-IIb
P05106 ITB3_HUMAN Homo sapiens Integrin beta-3
P05106 ITB3_HUMAN Homo sapiens Integrin beta-3
P08514 ITA2B_HUMAN Homo sapiens Integrin alpha-IIb
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