PDB Information

PDB3NAY
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Selective inhibition of PDK1 using an allosteric kinase inhibitor and RNAi impairs cancer cell migration and anchorage-independent growth of primary tumor lines
Nagashima, K., Shumway, S.D., Sathyanarayanan, S., Chen, A., Dolinski, B., Xu, Y., Keilhack, H., Nguyen, T., Wiznerowicz, M., Li, L., Lutterbach, B.A., Paweletz, C., Allison, T., Yan, Y., Munshi, S.K., Klippel, A., Kraus, M., Bobkova, E.V., Deshmukh, S., Xu, Z., Mueller, U., Szewczak, A.A., Pan, B.-S., Richon, V., Pollock, R., Blume-Jensen, P., Northrup, A., Andersen, J.N.
J.Biol.Chem.
HeaderTransferase
Released2010-06-02
Resolution2.600
CATH Insert Date23 Jan, 2011

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 24 Jan, 2011 Chopped
B 24 Jan, 2011 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3nayA01 17 Feb, 2011 3.30.200.20 Assigned
3nayA02 17 Feb, 2011 1.10.510.10 Assigned
3nayB01 17 Feb, 2011 3.30.200.20 Assigned
3nayB02 17 Feb, 2011 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O15530 PDPK1_HUMAN Homo sapiens 3-phosphoinositide-dependent protein kinase 1
O15530 PDPK1_HUMAN Homo sapiens 3-phosphoinositide-dependent protein kinase 1
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