PDB Information

PDB3N1W
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery.
Jahnke, W., Rondeau, J.M., Cotesta, S., Marzinzik, A., Pelle, X., Geiser, M., Strauss, A., Gotte, M., Bitsch, F., Hemmig, R., Henry, C., Lehmann, S., Glickman, J.F., Roddy, T.P., Stout, S.J., Green, J.R.
Nat.Chem.Biol.
HeaderTransferase/Transferase Inhibitor
Released2010-05-17
Resolution2.560
CATH Insert Date22 Aug, 2010

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
F 23 Aug, 2010 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
3n1wF00 15 Oct, 2010 1.10.600.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P14324 FPPS_HUMAN Homo sapiens Farnesyl pyrophosphate synthase