PDB Information

PDB3MY0
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
A small molecule targeting ALK1 prevents Notch cooperativity and inhibits functional angiogenesis.
Kerr, G., Sheldon, H., Chaikuad, A., Alfano, I., von Delft, F., Bullock, A.N., Harris, A.L.
Angiogenesis
HeaderTransferase
Released2010-05-08
Resolution2.650
CATH Insert Date15 Aug, 2010

PDB Images (73)

PDB Prints

PDB Chains (24)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2010 Chopped
B 16 Aug, 2010 Chopped
C 16 Aug, 2010 Chopped
D 16 Aug, 2010 Chopped
E 16 Aug, 2010 Chopped
F 16 Aug, 2010 Chopped
G 16 Aug, 2010 Chopped
H 16 Aug, 2010 Chopped
I 16 Aug, 2010 Chopped
J 16 Aug, 2010 Chopped
K 16 Aug, 2010 Chopped
L 16 Aug, 2010 Chopped
M 16 Aug, 2010 Chopped
N 16 Aug, 2010 Chopped
O 16 Aug, 2010 Chopped
P 16 Aug, 2010 Chopped
Q 16 Aug, 2010 Chopped
R 16 Aug, 2010 Chopped
S 16 Aug, 2010 Chopped
T 16 Aug, 2010 Chopped
U 16 Aug, 2010 Chopped
V 16 Aug, 2010 Chopped
W 16 Aug, 2010 Chopped
X 16 Aug, 2010 Chopped

CATH Domains (48)

Domain ID Date inserted into CATH Superfamily CATH Status
3my0A01 14 Oct, 2010 3.30.200.20 Assigned
3my0A02 14 Oct, 2010 1.10.510.10 Assigned
3my0B01 14 Oct, 2010 3.30.200.20 Assigned
3my0B02 14 Oct, 2010 1.10.510.10 Assigned
3my0C01 14 Oct, 2010 3.30.200.20 Assigned
3my0C02 14 Oct, 2010 1.10.510.10 Assigned
3my0D01 15 Oct, 2010 3.30.200.20 Assigned
3my0D02 15 Oct, 2010 1.10.510.10 Assigned
3my0E01 15 Oct, 2010 3.30.200.20 Assigned
3my0E02 15 Oct, 2010 1.10.510.10 Assigned
3my0F01 14 Oct, 2010 3.30.200.20 Assigned
3my0F02 14 Oct, 2010 1.10.510.10 Assigned
3my0G01 14 Oct, 2010 3.30.200.20 Assigned
3my0G02 14 Oct, 2010 1.10.510.10 Assigned
3my0H01 15 Oct, 2010 3.30.200.20 Assigned
3my0H02 15 Oct, 2010 1.10.510.10 Assigned
3my0I01 15 Oct, 2010 3.30.200.20 Assigned
3my0I02 15 Oct, 2010 1.10.510.10 Assigned
3my0J01 15 Oct, 2010 3.30.200.20 Assigned
3my0J02 15 Oct, 2010 1.10.510.10 Assigned
3my0K01 15 Oct, 2010 3.30.200.20 Assigned
3my0K02 15 Oct, 2010 1.10.510.10 Assigned
3my0L01 14 Oct, 2010 3.30.200.20 Assigned
3my0L02 14 Oct, 2010 1.10.510.10 Assigned
3my0M01 15 Oct, 2010 3.30.200.20 Assigned
3my0M02 15 Oct, 2010 1.10.510.10 Assigned
3my0N01 15 Oct, 2010 3.30.200.20 Assigned
3my0N02 15 Oct, 2010 1.10.510.10 Assigned
3my0O01 15 Oct, 2010 3.30.200.20 Assigned
3my0O02 15 Oct, 2010 1.10.510.10 Assigned
3my0P01 14 Oct, 2010 3.30.200.20 Assigned
3my0P02 14 Oct, 2010 1.10.510.10 Assigned
3my0Q01 15 Oct, 2010 3.30.200.20 Assigned
3my0Q02 15 Oct, 2010 1.10.510.10 Assigned
3my0R01 15 Oct, 2010 3.30.200.20 Assigned
3my0R02 15 Oct, 2010 1.10.510.10 Assigned
3my0S01 15 Oct, 2010 3.30.200.20 Assigned
3my0S02 15 Oct, 2010 1.10.510.10 Assigned
3my0T01 15 Oct, 2010 3.30.200.20 Assigned
3my0T02 15 Oct, 2010 1.10.510.10 Assigned
3my0U01 15 Oct, 2010 3.30.200.20 Assigned
3my0U02 15 Oct, 2010 1.10.510.10 Assigned
3my0V01 15 Oct, 2010 3.30.200.20 Assigned
3my0V02 15 Oct, 2010 1.10.510.10 Assigned
3my0W01 15 Oct, 2010 3.30.200.20 Assigned
3my0W02 15 Oct, 2010 1.10.510.10 Assigned
3my0X01 15 Oct, 2010 3.30.200.20 Assigned
3my0X02 15 Oct, 2010 1.10.510.10 Assigned

UniProtKB Entries (24)

Accession Gene ID Taxon Description
P37023 ACVL1_HUMAN Homo sapiens Serine/threonine-protein kinase receptor R3
P37023 ACVL1_HUMAN Homo sapiens Serine/threonine-protein kinase receptor R3
P37023 ACVL1_HUMAN Homo sapiens Serine/threonine-protein kinase receptor R3
P37023 ACVL1_HUMAN Homo sapiens Serine/threonine-protein kinase receptor R3
P37023 ACVL1_HUMAN Homo sapiens Serine/threonine-protein kinase receptor R3
P37023 ACVL1_HUMAN Homo sapiens Serine/threonine-protein kinase receptor R3
P37023 ACVL1_HUMAN Homo sapiens Serine/threonine-protein kinase receptor R3
P37023 ACVL1_HUMAN Homo sapiens Serine/threonine-protein kinase receptor R3
P37023 ACVL1_HUMAN Homo sapiens Serine/threonine-protein kinase receptor R3
P37023 ACVL1_HUMAN Homo sapiens Serine/threonine-protein kinase receptor R3
P37023 ACVL1_HUMAN Homo sapiens Serine/threonine-protein kinase receptor R3
P37023 ACVL1_HUMAN Homo sapiens Serine/threonine-protein kinase receptor R3
P37023 ACVL1_HUMAN Homo sapiens Serine/threonine-protein kinase receptor R3
P37023 ACVL1_HUMAN Homo sapiens Serine/threonine-protein kinase receptor R3
P37023 ACVL1_HUMAN Homo sapiens Serine/threonine-protein kinase receptor R3
P37023 ACVL1_HUMAN Homo sapiens Serine/threonine-protein kinase receptor R3
P37023 ACVL1_HUMAN Homo sapiens Serine/threonine-protein kinase receptor R3
P37023 ACVL1_HUMAN Homo sapiens Serine/threonine-protein kinase receptor R3
P37023 ACVL1_HUMAN Homo sapiens Serine/threonine-protein kinase receptor R3
P37023 ACVL1_HUMAN Homo sapiens Serine/threonine-protein kinase receptor R3
P37023 ACVL1_HUMAN Homo sapiens Serine/threonine-protein kinase receptor R3
P37023 ACVL1_HUMAN Homo sapiens Serine/threonine-protein kinase receptor R3
P37023 ACVL1_HUMAN Homo sapiens Serine/threonine-protein kinase receptor R3
P37023 ACVL1_HUMAN Homo sapiens Serine/threonine-protein kinase receptor R3