PDB 3ly2

PDB Information

PDB3LY2
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Water-soluble PDE4 inhibitors for the treatment of dry eye.
Govek, S.P., Oshiro, G., Anzola, J.V., Beauregard, C., Chen, J., Coyle, A.R., Gamache, D.A., Hellberg, M.R., Hsien, J.N., Lerch, J.M., Liao, J.C., Malecha, J.W., Staszewski, L.M., Thomas, D.J., Yanni, J.M., Noble, S.A., Shiau, A.K.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2010-02-26
Resolution2.600
CATH Insert Date02 May, 2010

PDB Images (17)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 03 May, 2010 Chopped
B 03 May, 2010 Chopped
C 03 May, 2010 Chopped
D 03 May, 2010 Chopped
E 03 May, 2010 Chopped
F 03 May, 2010 Chopped
G 03 May, 2010 Chopped
H 03 May, 2010 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3ly2A00 25 Apr, 2013 1.10.1300.10 Assigned
3ly2B00 25 Apr, 2013 1.10.1300.10 Assigned
3ly2C00 25 Apr, 2013 1.10.1300.10 Assigned
3ly2D00 25 Apr, 2013 1.10.1300.10 Assigned
3ly2E00 25 Apr, 2013 1.10.1300.10 Assigned
3ly2F00 25 Apr, 2013 1.10.1300.10 Assigned
3ly2G00 25 Apr, 2013 1.10.1300.10 Assigned
3ly2H00 25 Apr, 2013 1.10.1300.10 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
Q07343 PDE4B_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4B
Q07343 PDE4B_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4B
Q07343 PDE4B_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4B
Q07343 PDE4B_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4B
Q07343 PDE4B_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4B
Q07343 PDE4B_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4B
Q07343 PDE4B_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4B
Q07343 PDE4B_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4B