Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis.
Schnute, M.E., O'Brien, P.M., Nahra, J., Morris, M., Howard Roark, W., Hanau, C.E., Ruminski, P.G., Scholten, J.A., Fletcher, T.R., Hamper, B.C., Carroll, J.N., Patt, W.C., Shieh, H.S., Collins, B., Pavlovsky, A.G., Palmquist, K.E., Aston, K.W., Hitchcock, J., Rogers, M.D., McDonald, J., Johnson, A.R., Munie, G.E., Wittwer, A.J., Man, C.F., Settle, S.L., Nemirovskiy, O., Vickery, L.E., Agawal, A., Dyer, R.D., Sunyer, T.
Bioorg.Med.Chem.Lett.
