PDB 3k5f

PDB Information

PDB3K5F
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure-based design and synthesis of novel P2/P3 modified, non-peptidic beta-secretase (BACE-1) inhibitors.
Hanessian, S., Shao, Z., Betschart, C., Rondeau, J.M., Neumann, U., Tintelnot-Blomley, M.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2009-10-07
Resolution2.250
CATH Insert Date09 May, 2010

PDB Images (10)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 10 May, 2010 Chopped
B 10 May, 2010 Chopped
C 10 May, 2010 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
3k5fA01 13 Jun, 2010 2.40.70.10 Assigned
3k5fA02 13 Jun, 2010 2.40.70.10 Assigned
3k5fB01 13 Jun, 2010 2.40.70.10 Assigned
3k5fB02 13 Jun, 2010 2.40.70.10 Assigned
3k5fC01 13 Jun, 2010 2.40.70.10 Assigned
3k5fC02 13 Jun, 2010 2.40.70.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1