PDB 3irn
PDB Information
| PDB | 3IRN |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Trypanosoma cruzi |
| Primary Citation | Structural basis of antifolate inhibition of Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate Synthase
To be Published
|
| Header | Oxidoreductase, Transferase |
| Released | 2009-08-24 |
| Resolution | 2.600 |
| CATH Insert Date | 15 Aug, 2010 |
PDB Images (13)
3irn
PDB 3irn
3irnA
PDB Chain 3irnA
3irnB
PDB Chain 3irnB
3irnC
PDB Chain 3irnC
3irnD
PDB Chain 3irnD
3irnA01
CATH Domain 3irnA01
3irnA02
CATH Domain 3irnA02
3irnB01
CATH Domain 3irnB01
3irnB02
CATH Domain 3irnB02
3irnC01
CATH Domain 3irnC01
3irnC02
CATH Domain 3irnC02
3irnD01
CATH Domain 3irnD01
3irnD02
CATH Domain 3irnD02
PDB Prints
PDB Chains (4)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 16 Aug, 2010 | Chopped |
| B | 16 Aug, 2010 | Chopped |
| C | 16 Aug, 2010 | Chopped |
| D | 16 Aug, 2010 | Chopped |
CATH Domains (8)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 3irnA01 | 11 May, 2013 | 3.40.430.10 | Assigned |
| 3irnA02 | 11 May, 2013 | 3.30.572.10 | Assigned |
| 3irnB01 | 11 May, 2013 | 3.40.430.10 | Assigned |
| 3irnB02 | 11 May, 2013 | 3.30.572.10 | Assigned |
| 3irnC01 | 11 May, 2013 | 3.40.430.10 | Assigned |
| 3irnC02 | 11 May, 2013 | 3.30.572.10 | Assigned |
| 3irnD01 | 11 May, 2013 | 3.40.430.10 | Assigned |
| 3irnD02 | 11 May, 2013 | 3.30.572.10 | Assigned |
UniProtKB Entries (4)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| Q27793 | DRTS_TRYCR | Trypanosoma cruzi | Bifunctional dihydrofolate reductase-thymidylate synthase |
| Q27793 | DRTS_TRYCR | Trypanosoma cruzi | Bifunctional dihydrofolate reductase-thymidylate synthase |
| Q27793 | DRTS_TRYCR | Trypanosoma cruzi | Bifunctional dihydrofolate reductase-thymidylate synthase |
| Q27793 | DRTS_TRYCR | Trypanosoma cruzi | Bifunctional dihydrofolate reductase-thymidylate synthase |
